核苷与核苷酸|Nucleosides & Nucleotides-毕得医药

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核苷是糖胺，可以被认为是不含磷酸基的核苷酸。核苷由一个核苷酸(也称为氮基)和一个五碳糖(核糖或脱氧核糖)组成，而核苷酸由一个核苷酸、一个五碳糖和一个或多个磷酸基组成。在核苷中，碱基通过-糖苷键与核糖或脱氧核糖结合。核苷酸是有机分子，是构成核酸聚合物的单体单位，脱氧核糖核酸(DNA)和核糖核酸(RNA)，两者都是地球上所有生命形式中必不可少的生物分子。核苷酸是核酸的基本组成部分;它们由三个亚基分子组成:一个氮基、一个五碳糖(核糖或脱氧核糖)和至少一个磷酸基。核苷是含氮的碱和5碳的糖。因此，一个核苷加上一个磷酸基产生一个核苷酸。

1-((2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-((2R,4S,5S)-4-叠氮基-5-(羟甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮: BJS074112730516-87-199%; ￥214.005g

Sodium ((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate ((2R,3S,5R)-5-(4-氨基-2-氧代嘧啶-1(2H)-基)-3-羟基四氢呋喃-2-基)甲基磷酸二钠盐: BJS082409313085-50-298%; ￥804.001g

3',5'-TIPS-N-Ac-Cytidine N-(1-((6aR,8R,9R,9aS)-9-羟基-2,2,4,4-四异丙基四氢-6H-呋喃并[3,2-f][1,3,5,2,4]三氧杂二硅庚烷-8-基)-2-氧代-1,2-二氢嘧啶-4-基)乙酰胺: BJS867294485335-73-595%; ￥1197.005g

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (2R,3S,4R,5R)-2-(羟甲基)-5-(6-((3-甲基丁-2-烯-1-基)氨基)-2-(甲硫基)-9H-嘌呤-9-基)四氢呋喃-3,4-二醇: BJS516881420859-00-195%; ￥2098.005mg

2-Amino-9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-1,9-dihydro-6H-purin-6-one 2-氨基-9-((4aR,6R,7R,7aS)-2,7-二羟基-2-氧化四氢-4H-呋喃[3,2-][1,3,2]二氧膦杂己环-6-基)-1,9-二氢-6-嘌呤-6-酮: BJS56821927665-99-895%; ￥4364.00100mg

5-Bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 5-溴-1-((2R,3R,4R,5R)-3-氟-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮: BJS806166655612-18-599%; ￥1712.00250mg

((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate ((2R,3S,4R,5R)-3,4-二羟基-5-(6-羟基-9H-嘌呤-9-基)四氢呋喃-2-基)甲基磷酸二氢酯: BJS3156549131-99-799%; ￥17711.005g

N-(9-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide N-(9-((2R,3S,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-9H-嘌呤-6-基)苯甲酰胺: BJS072552679896-97-297%; ￥164.001g

4-Amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 4-氨基-5-溴-1-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2(1H)-酮: BJS83212103066-86-295%; ￥722.005g

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮: BJS497565050-89-598%; ￥65.0025g

((2R,3S,4R,5R)-3,4-Dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate ((2R,3S,4R,5R)-3,4-二羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基磷酸酯: BJS07508563590-47-497%; ￥2039.0050mg

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one 4-氨基-1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-(羟甲基)嘧啶-2(1H)-酮: BJS43116797226-77-999%; ￥1000.00100mg

((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate ((S)-3-氨基-3-羧丙基)(((2S,3S,4R,5R)-5-(6-氨基-9H-嘌呤-9-基)-3,4-二羟基四氢呋喃-2-基)甲基)(甲基)锍 4-甲基苯磺酸盐: BJS511060052248-03-098%; ￥250.00100mg

(2R,3R,4R,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol (2R,3R,4R,5R)-2-(6-(环戊基氨基)-9H-嘌呤-9-基)-5-(羟甲基)-3-甲基四氢呋喃-3,4-二醇: BJS9971223205171-06-895+%; ￥8495.001g

5-Chloro-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 5-氯-1-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮: BJS44910002880-89-995%; ￥18608.005g

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-甲基-2-硫代-2,3-二氢嘧啶-4(1H)-酮: BJS968544228585-51-597%; ￥13499.00250mg

2-Amino-9-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 2-氨基-9-((2R,3R,5S)-3-羟基-5-(羟甲基)四氢呋喃-2-基)-1H-嘌呤-6(9H)-酮: BJS20991023608-58-095%; ￥1329.00250mg

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-4-(甲基氨基)嘧啶-2(1H)-酮: BJS264071622882-02-699%; ￥15601.001g

((2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate ((2R,3S,5R)-3-羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基苯甲酸酯: BJS494457035898-29-495%; ￥407.00100mg

9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one 9-((2R,3R,4R,5R)-4-羟基-5-(羟甲基)-3-甲氧基四氢呋喃-2-基)-2-(甲氨基)-1,9-二氢-6H-嘌呤-6-酮: BJS6118045135023-21-198%; ￥1220.00100mg

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