核苷与核苷酸|Nucleosides & Nucleotides-毕得医药

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核苷是糖胺，可以被认为是不含磷酸基的核苷酸。核苷由一个核苷酸(也称为氮基)和一个五碳糖(核糖或脱氧核糖)组成，而核苷酸由一个核苷酸、一个五碳糖和一个或多个磷酸基组成。在核苷中，碱基通过-糖苷键与核糖或脱氧核糖结合。核苷酸是有机分子，是构成核酸聚合物的单体单位，脱氧核糖核酸(DNA)和核糖核酸(RNA)，两者都是地球上所有生命形式中必不可少的生物分子。核苷酸是核酸的基本组成部分;它们由三个亚基分子组成:一个氮基、一个五碳糖(核糖或脱氧核糖)和至少一个磷酸基。核苷是含氮的碱和5碳的糖。因此，一个核苷加上一个磷酸基产生一个核苷酸。

1-((2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-((2R,4S,5S)-4-叠氮基-5-(羟甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮: BJS074112730516-87-199%; ￥365.005g

((2R,3S,5R)-3-Acetoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate ((2R,3S,5R)-3-乙酰氧基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基乙酸酯: BJS43380526979-97-198%; ￥779.00250mg

3',5'-TIPS-N-Ac-Cytidine N-(1-((6aR,8R,9R,9aS)-9-羟基-2,2,4,4-四异丙基四氢-6H-呋喃并[3,2-f][1,3,5,2,4]三氧杂二硅庚烷-8-基)-2-氧代-1,2-二氢嘧啶-4-基)乙酰胺: BJS867294485335-73-595%; ￥1088.005g

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (2R,3S,4R,5R)-2-(羟甲基)-5-(6-((3-甲基丁-2-烯-1-基)氨基)-2-(甲硫基)-9H-嘌呤-9-基)四氢呋喃-3,4-二醇: BJS516881420859-00-195%; ￥2098.005mg

2-Amino-9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-1,9-dihydro-6H-purin-6-one 2-氨基-9-((4aR,6R,7R,7aS)-2,7-二羟基-2-氧化四氢-4H-呋喃[3,2-][1,3,2]二氧膦杂己环-6-基)-1,9-二氢-6-嘌呤-6-酮: BJS56821927665-99-895%; ￥4364.00100mg

(2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal (2R,3R,4R)-2,3,4,5-四羟基戊醛: BJS250152350-69-197%; ￥151.00500g

5-Bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 5-溴-1-((2R,3R,4R,5R)-3-氟-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮: BJS806166655612-18-598%; ￥1712.00250mg

((2R,3S,4R,5R)-3,4-Dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate ((2R,3S,4R,5R)-3,4-二羟基-5-(6-羟基-9H-嘌呤-9-基)四氢呋喃-2-基)甲基磷酸二氢酯: BJS3156549131-99-799%; ￥17711.005g

N-(9-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide N-(9-((2R,3S,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-9H-嘌呤-6-基)苯甲酰胺: BJS072552679896-97-297%; ￥164.001g

((2R,3S,4R,5R)-3,4-Dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate ((2R,3S,4R,5R)-3,4-二羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基磷酸酯: BJS07508563590-47-497%; ￥1854.0050mg

(2S,3R,4S,5R)-2-(5,6-Dimethyl-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (2S,3R,4S,5R)-2-(5,6-二甲基-1H-苯并[d]咪唑-1-基)-5-(羟甲基)四氢呋喃-3,4-二醇: BJS9837998132-13-895%; ￥5376.0050mg

((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate ((S)-3-氨基-3-羧丙基)(((2S,3S,4R,5R)-5-(6-氨基-9H-嘌呤-9-基)-3,4-二羟基四氢呋喃-2-基)甲基)(甲基)锍 4-甲基苯磺酸盐: BJS511060052248-03-098%; ￥250.00100mg

((2R,3S,5R)-3-Acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate ((2R,3S,5R)-3-乙酰氧基-5-(5-溴-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基乙酸酯: BJS12492236161-23-597%; ￥659.00250mg

((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)methanol ((2R,3S,5R)-5-(6-氨基-9H-嘌呤-9-基)-3-((叔丁基二甲基硅烷基)氧基)四氢呋喃-2-基)甲醇: BJS290185751549-31-698%; ￥7136.001g

(2R,3S,4S,5R)-2-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-carbonitrile hydrochloride (2R,3S,4S,5R)-2-(4-氨基-2-氧代嘧啶-1(2H)-基)-4-羟基-5-(羟甲基)四氢呋喃-3-甲腈盐酸盐: BJS0232856134665-72-898%; ￥8583.00100mg

(2R,3S,5S)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (2R,3S,5S)-5-(6-氨基-9H-嘌呤-9-基)-2-(羟甲基)四氢呋喃-3-醇: BJS03094003413-66-997%; ￥2316.0050mg

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-甲基-2-硫代-2,3-二氢嘧啶-4(1H)-酮: BJS968544228585-51-597%; ￥13499.00250mg

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-5-碘嘧啶-2(1H)-酮: BJS405583793265-81-798%; ￥25780.0050mg

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one 1-((2R,4S,5R)-4-羟基-5-(羟甲基)四氢呋喃-2-基)-4-(甲基氨基)嘧啶-2(1H)-酮: BJS264071622882-02-697%; ￥15601.001g

((2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate ((2R,3S,5R)-3-羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基苯甲酸酯: BJS494457035898-29-495%; ￥407.00100mg

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